Read e-book online 2008-2009 Basic and Clinical Science Course: Section 9: PDF
By Ramana S. Moorthy, MD
A dialogue of the medical method of uveitis results in widely rewritten chapters on noninfectious (autoimmune) and infectious sorts of uveitis. additionally coated are endophthalmitis, masquerade syndromes, and problems of uveitis. A dialogue on ocular involvement in AIDS has been up-to-date. The part on immunology describes the human immune reaction in phrases that make it hugely obtainable to readers.
Read or Download 2008-2009 Basic and Clinical Science Course: Section 9: Intraocular Inflammation and Uveitis (Basic and Clinical Science Course 2008-2009) PDF
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Additional info for 2008-2009 Basic and Clinical Science Course: Section 9: Intraocular Inflammation and Uveitis (Basic and Clinical Science Course 2008-2009)
Thus, pluripotential stem cells differentiate into various myeloid or lymphoid precursor cells, which then differentiate into monocyte precursors, T- and B-lymphocyte precursors, and so on. B lymphocytes mature within the bone marrow, whereas immature T lymphocytes exit the bone marrow and mature within the thymus. Mature Band T lymphocytes then exit into the blood, where they enter secondary lymphoid tissues. Granulocytes and monocytes exit the bone marrow directly as functional effectors, although some monocyte subpopulations can further differentiate in peripheral tissues.
Homing Memory also requires that lymphocytes demonstrate a complex migratory pattern called homing. Thus, lymphocytes pass from the circulation into various tissues, from which they subsequently depart, and then pass by way of lymphatics to reenter the circulation. Homing involves the variable interaction between lymphocytes and endothelial cells using multiple cell-adhesion molecules, which are discussed in Chapter 4. Usually, the major types oflymphocytes that migrate into tissue sites are memory lymphocytes that express higher levels of certain cell-adhesion molecules, such as the integrins, than do naive cells.
Immunoregulatory Stein-Streilein j, Streilein jw. Anterior chamber-associated immune deviation (ACAID): regulation, biological relevance, and implications for therapy. Int Rev Immunol. 2002;21:123-152. CHAPTER 3: Ocular CLINICAL Immune Responses. EXAMPLES3-4 Retinal transplantation Transplantation of retina or RPE is being investigated as a method for regenerating retinal function in various disorders. In experimental animals, subretinal transplantation of fetal retinal tissue or various kinds of RPE allografts often show longer survival than the same grafts implanted elsewhere, even without systemic immunomodulation.
2008-2009 Basic and Clinical Science Course: Section 9: Intraocular Inflammation and Uveitis (Basic and Clinical Science Course 2008-2009) by Ramana S. Moorthy, MD